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Experience exceptional care and cutting-edge technology at Dynasty Clinic.
Stem Cells Treatment in Dubai – Stem cells are unique human cells that give rise to functional cells. Stem cells are also known as “genius cells,” from which “sister chromatids” develop. These d cells have the potential to develop into new progenitor cells or specialized cells. Calcium ions, heart muscle cells, tissue muscle cells, brain cells, and blood platelets are examples of specialized cell types.
The following are the various sources of stem cells:
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Dr. Adeel Khan is an expert in musculoskeletal medicine, pain medicine and regenerative medicine.
Anti-aging refers to a range of products and treatments that can reduce the signs of aging on the skin, such as wrinkles, age spots, and sagging skin. These products and treatments work by nourishing and protecting the skin from the harmful effects of the environment and free radicals. Using anti-aging products and treatments has several benefits, including:
Plasmid therapy works by introducing plasmids, which are small, circular DNA molecules, into the body. These plasmids contain therapeutic genes that are designed to treat specific diseases. Once the plasmids enter the target cells, the genes are expressed, and the proteins they produce can help combat the disease.
The plasmids are usually delivered to the target cells using various methods, such as injections or inhalation. Once the plasmids are inside the cells, they start to replicate, creating more copies of themselves and producing the therapeutic proteins.
Targeted delivery: Plasmids can be engineered to target specific types of cells or tissues, allowing for more precise delivery of therapeutic genes.
Low risk of immune response: Plasmids are non-infectious and non-toxic, and are less likely to trigger an immune response compared to other gene delivery methods.
Long-lasting effects: Plasmids can persist in cells for extended periods of time, allowing for sustained expression of therapeutic genes
Customizability: Plasmids can be modified to express different therapeutic genes or combinations of genes, making them a versatile tool in gene therapy.
Minimal off-target effects: Plasmids have been shown to have minimal off-target effects, reducing the risk of unintended consequences
Minicircle Technology is a DNA modification tool that can be used for genetic therapy in humans. Minicircles are small, circular DNA loops that are cost-effective and completely reversible. Unlike viral vectors, minicircles are pure DNA and do not require complex and expensive production techniques.
Minicircles are produced in E. coli, the world’s most scalable biopharmaceutical manufacturing organism. The therapy has a high transformation efficiency and is uniquely reversible since it only affects cells at the site of injection, which can be dissolved using a US FDA-approved injectable treatment for cosmetic fat reduction called Kybella.
Follistatin is a widely researched gene therapy that can lead to a higher quality of life for humans by addressing the primary problems of aging such as cardiovascular disease, muscle wasting, bone loss, hair loss, inflammation, cancer, obesity, and diabetes.
The clinical outcomes of follistatin gene therapy include doubling of skeletal muscle mass, increased bone density, improved serum lipid profiles, reduction of inflammation, suppression of metastasis, and more.
Follistatin gene therapy is safe and has no negative side effects, and a conservative dosing regime has shown an increase in follistatin serum concentration of 55%. However, the current problem with follistatin gene therapy is that it is too expensive.
The discovery of the N6 antibody in 2016 was a breakthrough in the search for an HIV cure. Since then, several antibodies have been prototyped for HIV treatment. A combination of two antibodies was found to be effective in curing six out of eleven monkeys in a 2018 trial. A phase 1b human clinical trial also showed that two HIV antibodies were capable of providing complete suppression until the end of the study in 2018.
However, antibody infusion therapy has its problems, such as being expensive and requiring frequent hospital visits. A gene therapy approach is expected to solve these issues by producing antibodies at a constant rate from the patient’s own body. This approach is also expected to be applicable to other infectious diseases, autoimmune diseases, and some forms of cancer.
Follistatin-344 Plasmid Therapy is a gene therapy that aims to increase muscle growth and strength by enhancing the production of follistatin, a protein that regulates muscle growth. Follistatin-344 is a synthetic version of the naturally occurring protein follistatin. The therapy involves injecting a plasmid (a small DNA molecule) that carries the gene for follistatin-344 into muscle tissue.
Follistatin-myostatin complex has been the most researched gene therapy application since the late 1980s, and it is now considered the safest and most broadly applicable gene therapy in the world. Follistatin activates the FOXO3 transcription pathway, improving DNA repair, stem cell maintenance, oxidative stress response, and autophagy, which could increase the healthy lifespan of humans.
The highest levels of follistatin have been found in pregnant women, and no negative side effects have been noted in scientific literature after years of research on follistatin gene therapy. Follistatin plasmid injection is designed to be administered via a subcutaneous fat injection, having a continuous expression duration of approximately 1.5 years. The plasmid injection is non-inflammatory, and there is a genetic killswitch encoded into the DNA where the plasmids are destroyed in the presence of the common antibiotic tetracycline.
While the therapy is generally considered safe, there is still much that is unknown about its long-term effects. More research is needed to fully understand the potential risks and side effects.
Follistatin-344 Plasmid Therapy is being studied as a potential treatment for muscle wasting diseases, as well as a way to enhance muscle growth in athletes and bodybuilders.
The therapy involves injecting a plasmid carrying the gene for follistatin-344 into muscle tissue.
Animal studies have shown that the therapy can increase muscle mass and strength in as little as two weeks. However, more research is needed to fully understand how quickly results can be seen in humans.
Follistatin-344 Plasmid Therapy is still in the early stages of research and has not yet been approved for widespread use. It is important to consult with a medical professional before undergoing any experimental treatments.